Docentes
Richard E. Frye. M.D., Ph.D.
Neurólogo
Phoenix AZ - U.S.A.
Nneurólogo infantil con
experiencia en trastornos del desarrollo neurológico y neurometabólico. Recibió
un doctorado y un doctorado en fisiología y biofísica de la Universidad de
Georgetown y completó su residencia y beca de neurología infantil en neurología
conductual y discapacidades de aprendizaje en la Universidad de Harvard /
Children's Hospital Boston.
Es autor de más de 150 publicaciones revisadas por pares y capítulos de libros, y es miembro de varios consejos editoriales. Ha realizado varios ensayos clínicos que demuestran la eficacia de tratamientos seguros y novedosos que se dirigen a las anormalidades fisiológicas subyacentes en niños con TEA. Es Jefe de Trastornos del Neurodesarrollo en el Instituto Neurológico de Barrow en el Phoenix Children's Hospital.
Dr.
Richard Frye is a Child Neurologist with expertise in neurodevelopmental and
neurometabolic disorders. He received an MD and PhD in Physiology and
Biophysics from Georgetown University and completed his Child Neurology Residency
and Fellowship in Behavioral Neurology and Learning Disabilities at Harvard
University/Children's Hospital Boston. He has authored over 150 peer-reviewed
publications and book chapters, and serves on several editorial boards. He has
conducted several clinical trials demonstrating the efficacy of safe and novel
treatments that target underlying physiological abnormalities in children with
ASD. He is the Chief of Neurodevelopmental Disorders at
the Barrow Neurological Institute at Phoenix Children's Hospital.
Present
Title
• Professor
of Child Health and Neurology
•
Director
of Autism and Fragile X Programs
•
Chief,
Division of Neurodevelopmental Disorders
Field of study
• 1982-86: B.A. - Psychobiology / Computer Science - Long
Island University, Greenvale, NY
• 1988-91: M.S. - Biomedical
Science/ Biostatistics - Drexel University, Philadelphia, PA
• 1991-98: Ph.D. - Physiology
and Biophysics - Georgetown University, Washington, DC
• 1991-98: M.D. - Medicine - Georgetown
University, Washington, DC
Postgraduate
Training
• 5/1998-6/2000: Resident in Pediatrics, Jackson
Memorial Hospital, University of Miami, Miami, FL
• 7/2000-6/2003:
Resident in Neurology, Children's
Hospital Boston, Harvard University, Boston, MA
• 7/2003-6/2005:
Fellow in Behavioral Neurology and
Learning Disabilities, Children's Hospital Boston, Harvard University, Boston,
MA
• 7/2004-6/2005: Fellow in
Psychology, Department of Psychology, Boston University, Boston,
MA
Academic
Appointments
• 7/2005-6/2006: Assistant Professor, Department of Pediatrics and Neurology,
University of Florida, Gainesville, FL
• 7/2005-6/2006: Co-Medical
Director, Multidisciplinary Diagnostic and Training
Program,
University
of Florida, Gainesville, FL
• 1/2006-6/2006: Co-Director,
University of Florida School Problems Clinic,
University
of Florida, Gainesville, FL
• 7/2006-9/2011: Assistant
Professor, Department of Pediatrics, Division of Child and
Adolescent
Neurology and The Children's Learning Institute; Department of Neurology,
University of Texas, Houston, TX
• 1/2007-9/2011: Member, Center for Clinical and
Translational Science, University of Texas,
Houston, TX
• 1/2007-9/2011: Director, Medically-Based Autism
Clinic, Department of Pediatrics, University of Texas,
Houston, TX
• 1/2010-9/2011: Director,
Laboratory for the Biological Basis of Neurodevelopmental Disorders,
University of Texas, Houston, TX
• 10/2011-12/2017: Associate
Professor, Department of Pediatrics, University of Arkansas for Medical
Sciences, Little Rock, Arkansas
• 10/2011-12/2017: Director
of Autism Research, Arkansas Children's Hospital Research Institute,
Little Rock, Arkansas
• 3/2012-12/2017: Neurology
Consultant, Autism Treatment Network, University of Arkansas for
Medical
Sciences, Little Rock, Arkansas
• 6/2012-12/2017: Director,
Autism Multispecialty Clinic, Arkansas Children's Hospital,
Little Rock, Arkansas
• 10/2013-12/2017: Co-Director,
Neurometabolic Clinic, Arkansas Children's Hospital,
Little Rock, Arkansas
• 8/2014-12/2017: Member,
Center for Applied Research and Evaluation, Arkansas Children's Hospital,
Little Rock, Arkansas
• 1/2017-12/2017: Director,
Neuroimmune Clinic, Arkansas Children's Hospital, Little Rock, Arkansas
• 12/2017-: Professor of Child Health,
University of Arizona College of
Medicine - Phoenix, Phoenix AZ
• 12/2017-: Chief, Section on Neurodevelopmental
Disorders, Barrow Neurological Institute,
Phoenix Children's Hospital,
Phoenix AZ
• 12/2017-: Director, Neurodevelopmental and Mitochondrial Disorders Research
Laboratory,
University of Arizona College of
Medicine - Phoenix, Phoenix AZ
• 12/2017-: Director, Autism Program, Barrow Neurological Institute,
Phoenix Children's Hospital, Phoenix
AZ
• 1/2018-5/2019: Director, Down Syndrome Program, Barrow Neurological Institute,
Phoenix Children's Hospital,
Phoenix AZ
• 4/2018-: Professor of Neurology, Department of Neurology, Barrow
Neurological Institute,
Phoenix Children's Hospital,
Phoenix AZ
• 5/2018-: Director, Fragile X Syndrome Program, Barrow Neurological
Institute,
Phoenix Children's Hospital,
Phoenix AZ
• 12/2018-: Clinical Professor, Department of Neurology,
Creighton University School of
Medicine, Omaha, NE
• 9/2019-: Professor of Pediatric Neurology, Mayo Clinic Alix School of
Medicine, Scottsdale,
AZ
Hospital
Appointments
• 7/2005-6/2006: Shands Hospital, University of Florida, Gainesville, FL
• 7/2006-9/2011: Hermann Memorial Hospital, University of Texas Health
Science Center, Houston, TX
• 12/2011-12/2017: University of Arkansas for Medical Sciences, Little
Rock, AR
• 1/2012-12/2017: Arkansas Children's Hospital, Little Rock, AR
• 12/2017-: Phoenix Children's Hospital, Phoenix AZ
Medical Licenses
• Arizona - 54974 - Active - 09/28/2017-12/15/2020
• Arkansas - E7303 - Unlimited 12/02/2011-12/31/2018 (Inactive)
• Kentucky - 51376 - 06/21/2018-02/28/2019
(Inactive
• Texas - M5715 - Full Medical License - 03/12/2007-11/30/2017 (Inactive)
Honors
and Awards
• 1991: Distinguished Service Award. Smell and
Taste Research Center, University of Pennsylvania.
• 1991-1998:
Ruggles Scholarship. Georgetown
University Medical School, Washington, DC
• 1993-1996:
Pre-Doctoral Fellowship. National
Biomedical Research Foundation, Washington, D.C.
• 1994-1995:
ARCS Award, Achievement Rewards for
College Scientists Foundation, Washington, D.C..
• 1998: Lawrence S. Lilienfield, MD, PhD Award,
Department of Physiology and Biophysics, Georgetown University Graduate School
of Arts and Sciences
• 2003-2005: Charles King Foundation Post-Doctoral
Fellowship, Medical Foundation, Boston, MA
• 2006: Nelson
Butters Award, International
Neuropsychological Society,Columbus, Ohio
• 2013: Arkansas Biomedical Institute New
Investigator Award, University of Arkansas for
Medical
Sciences, Little Rock AR
• 2018: Ranked #2 of the Top Ten Autism
Research of 2018, Autism Speaks, New York NY
Board Certifications
•
10/2004-9/2024: Board Certification in
General Pediatrics
•
5/2004-4/2024: Board Certification in
Neurology with Special Competence in Child Neurology
• 3/2016-3/2020: Certified Principal Investigator, Association of Clinical Research
Professionals
Specialized Coursework
in Clinical Trials and Translational Research
•
2016: Advanced GCP: Assessing Compliance
Risk, Association for Clinical Research
Professionals,
Arkansas Children's Hospital, Little Rock, AR
•
2009: Clinical Trials. University
of Texas Health Science Center, Houston, TX
•
2009: Navigating the Regulatory Highway.
University of Texas Health Science Center, Houston, TX
•
2007: Translational Research. University
of Texas Health Science Center, Houston, TX
•
2004: Introduction of Clinical Research, Children's Hospital Boston,
Boston, MA
Specialized Training
in Neuroimaging
•
2010: ANFI Bootcamp. University of
Texas Health Science Center, Houston, TX
•
2005:
Near-Infrared
Spectroscopy-Diffuse Optical Imaging Visiting Fellowship,
MGH/MIT/HMS
Martinos Imaging Center, Charlestown, MA
•
2003: Mini-Fellowship in Transcranial Magnetic Stimulation, Laboratory for Magnetic Brain
Stimulation, Beth-Israel Deaconess Medical Center, Boston, MA
•
2003: Siemens IDEA Software for Magnetic Resonance Sequence and Image Processing
Development
Training, MGH/MIT/HMSMartinos
Imaging Center, Charlestown, MA
•
2003: Basic and Advanced Magnoencepholography Operations and Data Analysis,
Martinos
Imaging Center, Charlestown, MA
•
2003: fMRI Statistics, Martinos
Imaging Center, Charlestown, MA
Specialized Training
in Cognitive Neuroscience
• 2005: Summer Institute for Cognitive Neuroscience, Dartmouth College, Hanover, NH
Specialized Training
in Autism Diagnosis and Screening
•
2008: Autism Diagnostic Observation
Schedule Clinical and Research Training, University
of Texas Health Science Center, Houston, TX
•
2019: RITA-T, Phoenix Children's
Hospital, Phoenix AZ
Specialized Training
in Complex and Non-linear System
•
1996: Complex Systems Summer School. Sante Fe Institute, Sante
Fe, NM
•
1994: Noise Fluctuation Analysis: Characteristics of Ion-Channel Signal
Ensemble. Department
of Physiology and Biophysics, Georgetown
University, Washington, DC
•
1993: Origins of Order: Non-Linear Systems and Evolution. Department of
Chemistry,Georgetown
University,
Washington, DC
Editorial
Board
• 2020- : Journal of Translational
Genetics and Genomics, Editorial Board
• 2019- : Annals of Translational
Medicine, Editorial Board
• 2016- : Clinical Medicine Insights:
Pediatrics, Editorial Board
• 2016- : Journal of Autism and Epilepsy,
Editorial Board
• 2013- : American Journal of
Neuroscience Research, Advisory Editorial Board
• 2013- : Frontiers in Child
Health and Human Development, Associate Editor
• 2013-: Journal
of Central Nervous System Disease, Editorial Board
• 2013- : Frontiers in Neuropsychiatric
Imaging and Stimulation, Review Editorial Board
• 2012- : Scientific Reports
Editorial Board
• 2012- : OA Autism, Advisory Board
Member
• 2012- : The North American Journal of
Medicine and Science, Editorial Board
• 2007- : Computers in Biology and
Medicine, Editorial Board
• 2007: Journal
of Pediatric Neurology, USA Editor
• 2005-2007: Computers
in Biology and Medicine, Associate Editor
• 2006-2007:
Journal of Pediatric Neurology, Assistant Editor
Publication Indices
• h-index:
48
• i10-index: 117
• Citations: 8,005
Special Issue Guest Editor
• Neuroconnectivity, Computers in Biology and Medicine, Dec 2011; Volume 41,
Issue 12
• Mitochondrial,
Metabolic and Nutritional Disorders Associated with Neurodevelopmental
Disorders,Journal of Pediatric Biochemistry, Dec 2012; Volume 2, Issue 4.
• The
Microbiome in Autism Spectrum Disorder, Microbial
Ecology in Health and Disease, S1, 2015
• Metabolic and
Immune Disorders Associated with Psychiatric Disease: Potential Etiology and
Pathway for Treatment, Frontiers in Psychiatry, Section on Molecular Psychiatry, in
press
• Comorbidity and
Autism Spectrum Disorder, Frontiers in Psychiatry, Section on Child and Adolescent
Psychiatry, in press.
• Secondary vs
Idiopathic Autism, Frontiers in Psychiatry, Section on Child and Adolescent
Psychiatry, in press.
• Advances
in the Diagnosis and Treatment of Autism Spectrum Disorder: Part 1, Seminars
in Pediatric Neurology, in press, expected May 2020.
• Advances
in the Diagnosis and Treatment of Autism Spectrum Disorder: Part 2, Seminars
in Pediatric Neurology, in press, expected September 2020.
Reviewer:
Acta
Paediatrica, Autism Research, Biological Psychiatry, BMC
Complementary and Alternative Medicine, BMC Psychiatry, Clinical
Chemistry and Laboratory Medicine, Clinical Therapeutics, Developmental
Cognitive Neuroscience, Developmental Medicine and Child
Neurology, Developmental
Neuroscience, Epilepsy Research, Environmental
Science and Pollution Research, Expert Opinion On Therapeutic Targets, Genes, Frontiers in Child
and Neurodevelopmental Psychiatry, Frontiers in Experimental Pharmacology and
Drug Discovery, Frontiers in Epilepsy, Frontiers in Neuropsychiatric Imaging
and Stimulation, Brain and Behavior, Headache, International
Journal of Environmental Research and Public Health, International
Journal of Molecular Sciences, Journal of Autism and Developmental Disorders, Journal of the International Neuropsychological Society, Journal
of Neurochemistry, Journal of Neuroinflammation, Journal of
Pediatric Infectious Disease, Journal of Psychosomatic Research, Molecular Basis of Disease, Molecular
Psychiatry, Neurobiology of Aging, Neuroimage, Neurology,
Neuropsychologia, Neuropsychopharmacology, Neuroscience
and Biobehavioral Reviews, Neuroscience Letters, New England
Journal of Medicine, Pediatrics, Prague Medical Report, Psychiatry Research, Redox Biology, Scientific Reports, Transactions on
Biomedical Engineering